Editorial
The treatment of hyponatremia: First, do no harm

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References (30)

  • MD Norenberg et al.

    Association between rise in serum sodium and central pontine myelinolysis

    Ann Neurol

    (1982)
  • RD Adams et al.

    Central pontine myelinolysis

    Arch Neurol Psychiatry

    (1959)
  • DG Wright et al.

    Pontine and extrapontine myelinolysis

    Brain

    (1979)
  • RH Sterns et al.

    Osmotic demyelination syndrome following correction of hyponatremia

    N Engl J Med

    (1986)
  • JE Brunner et al.

    Central pontine myelinolysis and pontine lesions after rapid correction of hyponatremia: a prospective magnetic resonance imaging study

    Ann Neurol

    (1990)
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