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Prediction of hemorrhage during long-term oral coumarin anticoagulation by excessive prothrombin ratio

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    Several patient characteristics are associated with higher odds of bleeding during anticoagulation therapy. The patient factor most consistently predictive of major bleeding is a history of bleeding (especially GI bleeding).162,208,273 Other factors associated with a higher risk of bleeding include advanced age; the presence of a serious comorbid condition, such as cancer, renal insufficiency, liver disease, arterial hypertension, and prior stroke; alcohol abuse; and the use of concomitant therapies, in particular antiplatelet drugs.162,203,204,207,303

  • Spontaneous Intracerebral Hemorrhage

    2009, Stroke in Children and Young Adults: Expert Consult - Online and Print
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