References
Bailey DG, Spence JD, Munoz C, Arnold JM (1991) Interaction of citrus juices with felodipine and nifedipine. Lancet 337:268–269
Egashira K, Fukuda E, Onga T et al. (2003) Pomelo-induced increase in the blood level of tacrolimus in a renal transplant patient. Transplantation 75:1057
Fukatsu S, Fukudo M, Masuda S et al. (2006) Delayed effect of grapefruit juice on pharmacokinetics and pharmacodynamics of tacrolimus in a living-donor liver transplant recipient. Drug Metab Pharmacokinet 21:122–125
Egashira K, Ohtani H, Itoh S et al. (2004) Inhibitory effects of pomelo on the metabolism of tacrolimus and the activities of CYP3A4 and P-glycoprotein. Drug Metab Dispos 32:828–833
Kane GC, Lipsky JJ (2000) Drug-grapefruit juice interactions. Mayo Clin Proc 75:933–942
Lohezic-Le Devehat F, Marigny K, Doucet M, Javaudin L (2002) Grapefruit juice and drugs: a hazardous combination? Therapie 57:432–445
Monnier G, Charpiat B, Serratrice F, Bossaert S, Fourcade N, Ducerf C (2003) Evaluation of drug therapy knowledge in liver transplant patients after pharmacy counseling. Therapie 58:305–311
FK506 Kidney Transplant Study Group (1994) Early phase II study of FK506 (tacrolimus) for kidney transplantation. Jpn J Transplant 29:294–313
FK506 Kidney Transplant Study Group (1994) Late phase II study of FK506 (tacrolimus) for kidney transplantation. Jpn J Transplant 29:614–631
FK506 Kidney Transplant Study Group (1994) Phase III study of FK506 (tacrolimus) for kidney transplantation. Jpn J Transplant 29:650–681
Seino Y, Hori M, Sonoda T (2003) Multicenter prospective investigation on cardiovascular adverse effects of tacrolimus in kidney transplantations. Cardiovasc Drugs Ther 17:141–149
Acknowledgements
We thank Dr. Vagneur and Pr. Descotes for helpful comments.
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None declared; funding: no extra funding.
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DP and BC conceived the idea, prepared the manuscript, reviewed the literature and edited the report. TV provided expert guidance throughout the preparation of the manuscript and reviewed the report. MG and CD were responsible for the patient care. All authors have read and approved the final manuscript.
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Peynaud, D., Charpiat, B., Vial, T. et al. Tacrolimus severe overdosage after intake of masked grapefruit in orange marmalade. Eur J Clin Pharmacol 63, 721–722 (2007). https://doi.org/10.1007/s00228-007-0323-3
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DOI: https://doi.org/10.1007/s00228-007-0323-3