Hospital length of stay and level of care for patients admitted to hospital with multisystem inflammatory syndrome in children, according to time of admission
| Variable | No. (%)* of patients admitted Mar. 1 to Oct. 31, 2020 | No. (%)* of patients admitted Nov. 1, 2020, to Mar. 7, 2021 | ||||
|---|---|---|---|---|---|---|
| Confirmed n = 28 | Probable n = 92 | All n = 120 | Confirmed n = 78 | Probable n = 34 | All n = 112 | |
| Duration of fever before admission, d, median (IQR) | 5 (3–6) | 5 (3–6) | 5 (3–6) | 4 (3–5) | 5 (3–6) | 4 (3–6) |
| Total duration of fever, d, median (IQR) | 7 (6–9) | 6.5 (5–9.5) | 7(5–9) | 5.5 (4–8) | 6 (6–10) | 6 (4–8) |
| Duration of admission, d, median (IQR) | 8 (6.5–10) | 5 (3–7) | 5 (4–8) | 6 (4–8) | 7 (4–12) | 6 (4–9) |
| Highest level of care | ||||||
| Ward admission | 18 (64.3) | 79 (85.9) | 97 (80.8) | 39 (50.0) | 23 (67.6) | 62 (55.4) |
| No supplemental oxygen | 14 (50.0) | 76 (82.6) | 90 (75.0) | 33 (42.3) | 20 (58.9) | 53 (47.3) |
| Supplemental oxygen | 4 (14.3) | 3 (3.3) | 7 (5.8) | 6 (7.7) | 3 (8.8) | 9 (8.0) |
| ICU admission | 10 (35.7) | 13 (14.1) | 23 (19.2) | 39 (50.0) | 11 (32.4) | 50 (44.6) |
| Observation with or without supplemental oxygen | 5 (17.8) | 2 (2.2) | 7 (5.8) | 11 (14.1) | 4 (11.8) | 15 (13.4) |
| Vasopressors with or without supplemental oxygen | 3 (10.7) | 6 (6.5) | 9 (7.5) | 19 (24.4) | 6 (17.6) | 25 (22.3) |
| Noninvasive ventilation and vasopressors | 0 (0) | 0 (0) | 0 (0) | 3 (3.8) | 1 (2.9) | 4 (3.6) |
| Mechanical ventilation, no vasopressors | 0 (0) | 1 (1.1) | 1 (0.8) | 1 (1.3) | 0 (0) | 1 (0.9) |
| Mechanical ventilation and vasopressors | 2 (7.1) | 1 (1.1) | 3 (3.3) | 4 (5.1) | 0 (0) | 4 (3.6) |
| Admission not for MIS-C | 0 (0) | 3 (3.3) | 3 (3.3) | 1 (1.3) | 0 (0) | 1 (0.9) |
| Treatment† | ||||||
| Intravenous immunoglobulin | 25 (89.3) | 69 (75.0) | 94 (78.3) | 68 (87.2) | 32 (94.1) | 100 (89.3) |
| Corticosteroids | 12 (42.8) | 37 (40.2) | 49 (40.8) | 57 (73.1) | 20 (58.8) | 77 (68.8) |
| Anakinra | 0 (0) | 3 (3.3) | 3 (3.3) | 3 (3.8) | 4 (11.8) | 7 (6.2) |
| None of the above | 2 (7.1) | 17 (18.5) | 19 (15.8) | 4 (5.1) | 1 (2.9) | 5 (4.5) |