Laboratory investigations during hospital admission*
| Investigation | 8 days postvaccine | 11 days postvaccine | 20 days postvaccine | Reference range |
|---|---|---|---|---|
| Creatinine, μmol/L | 69 | 67 | 66 | 58–110 |
| Urea, mmol/L | 1.8 | – | – | 2.7–6.7 |
| Sodium, mmol/L | 143 | 142 | 140 | 135–145 |
| Potassium, mmol/L | 3.3 | 5.3 | 3.7 | 3.5–5 |
| Chloride, mmol/L | 108 | 110 | 105 | 95–110 |
| Magnesium, mmol/L | 0.89 | 0.89 | 0.81 | 0.70–1.10 |
| Phosphate, mmol/L | 1.72 | 1.78 | 1.85 | 0.90–1.52 |
| Calcium, mmol/L | 2.12 | 2.33 | 2.30 | 2.10–2.60 |
| Albumin, g/L | 36 | 37 | 36 | 35–50 |
| Creatine kinase, U/L | 203 088 | 586 647 | 5772 | 30–150 |
| Hemoglobin, g/L | 129 | 126 | 99 | 115–165 |
| Mean corpuscular volume, fL | 86.1 | 90.1 | 94.1 | 82–99 |
| Platelets, × 109/L | 236 | 282 | 266 | 150–400 |
| Leukocytes, × 109/L | 9.6 | 10.8 | 6.7 | 4–11 |
| Lymphocytes, × 109/L | 1.9 | 2.5 | 2.3 | 1.5–4 |
| Neutrophils, × 109/L | 7.3 | 8.0 | 4.0 | 2–7.5 |
| Venous blood gas | ||||
| pH | 7.37 | 7.42 | 7.42 | 7.32–7.42 |
| pCO2, mm Hg | 44 | 47 | 46 | 38–50 |
| Bicarbonate, mmol/L | 25 | 31 | 30 | 24–30 |
| Liver enzymes | ||||
| Aspartate aminotransferase, U/L | 673 | 1376 | 109 | 18–34 |
| Alanine aminotransferase, U/L | 68 | 191 | 94 | 0–34 |
| γ-Glutamyl transferase, U/L | 27 | 42 | – | < 37 |
| Alkaline phosphatase, U/L | 96 | 96 | – | 38–126 |
| Total bilirubin, μmol/L | 8 | 11 | – | < 21 |
| Urinalysis | ||||
| Blood | 3+ | – | – | Negative |
| Protein | Negative | – | – | Negative |
| Ketones | Negative | – | – | Negative |
| Glucose | Negative | Negative | ||
Note: ANA = antinuclear antibody, anti = antibody, ANCA = antineutrophil cytoplasmic antibody, AU = arbitrary units, HMG-CoA = 3-hydroxy-3-methylglutaryl–coenzyme A, MDA5 = melanoma differentiation–associated gene 5, pCO2= partial pressure of carbon dioxide, SRP = signal recognition particle, TIF1 = transcription intermediary factor 1.
↵* Investigations for autoimmune markers (ANA screen, anti-Mi-2-α, anti-Mi-2-β, anti-TIF1-γ, anti-MDA5, anti-NXP2, anti-SAE1, anti-Ku, anti-PM/Scl-100, anti-PM/Scl-75, anti-Jo1, anti-SRP, anti-PL-7, anti-PL-12, anti-OJ, anti-Ro-52, anti-HMG-CoA reductase) were all negative, aside from P-ANCA and C-ANCA (both < 0.2 AU/mL at day 11 and < 1.0 AU/mL at day 20).