Common toxidromes
| Toxidrome | Temp | BP | HR | RR | Pupils | Mental status | Other |
|---|---|---|---|---|---|---|---|
| Opioids | ↓ | ↓ | ↓ | ↓ | ↓ | Depressed | Hyporeflexia |
| Sedative-hypnotic | −/↓ | ↓ | ↓ | ↓ | −/↓ | Depressed | Hyporeflexia |
| Anticholinergic | ↑ | −/↑ | ↑ | − | ↑ | Agitated delirium | Dry mucous membranes and skin, urinary retention |
| Sympathomimetic | ↑ | ↑ | ↑ | ↑ | ↑ | Agitated delirium | Tremor, seizures, diaphoresis |
| Serotonin toxicity | −/↑ | ↑ | ↑ | −/↑ | −/↑ | Agitated delirium | Hyperreflexia, clonus, tremor, seizures |
| Neuroleptic malignant syndrome | ↑ | ↑/↓ | ↑ | −/↑ | − | Agitated delirium | Rigidity |
Note: BP = blood pressure, HR = heart rate, RR = respiratory rate, temp = temperature.