Characteristics of study cohort by variant of concern status
| Variable | No. (%) of patients* | p value† | |||
|---|---|---|---|---|---|
| Total n = 212 326 | VOC not detected n = 43 417 | N501Y-positive VOC n = 162 920 | Probable Delta VOC n = 5989 | ||
| Hospitalized | 11 038 (5.2) | 1914 (4.4) | 8775 (5.4) | 349 (5.8) | < 0.001 |
| Admitted to ICU | 2324 (1.1) | 337 (0.8) | 1897 (1.2) | 90 (1.5) | < 0.001 |
| Died | 1820 (0.9) | 384 (0.9) | 1396 (0.9) | 40 (0.7) | 0.23 |
| Sex, male | 107 582 (50.7) | 22 023 (50.7) | 82 505 (50.6) | 3054 (51.0) | 0.84 |
| Age, yr | < 0.001 | ||||
| < 10 | 15 266 (7.2) | 3016 (6.9) | 11 732 (7.2) | 518 (8.6) | |
| 10–19 | 25 390 (12.0) | 5209 (12.0) | 19 508 (12.0) | 673 (11.2) | |
| 20–29 | 43 648 (20.6) | 8612 (19.8) | 33 640 (20.6) | 1396 (23.3) | |
| 30–39 | 35 983 (16.9) | 7117 (16.4) | 27 768 (17.0) | 1098 (18.3) | |
| 40–49 | 31 768 (15.0) | 6198 (14.3) | 24 769 (15.2) | 801 (13.4) | |
| 50–59 | 29 972 (14.1) | 6287 (14.5) | 22 920 (14.1) | 765 (12.8) | |
| 60–69 | 18 108 (8.5) | 3971 (9.1) | 13 664 (8.4) | 473 (7.9) | |
| 70–79 | 8018 (3.8) | 1892 (4.4) | 5944 (3.6) | 182 (3.0) | |
| ≥ 80 | 4173 (2.0) | 1115 (2.6) | 2975 (1.8) | 83 (1.4) | |
| Vaccination status | |||||
| Partially vaccinated | 72 838 (34.3) | 169 327 (39.0) | 54 211(33.3) | 1700 (28.4) | < 0.001 |
| Fully vaccinated | 945 (0.4) | 142 (0.3) | 732 (0.4) | 71 (1.2) | < 0.001 |
| Comorbidity‡ | 10 805 (5.1) | 2940 (6.8) | 7547 (4.6) | 318 (5.3) | < 0.001 |
| Pregnant | 555 (0.3) | 124 (0.3) | 410 (0.2) | 21 (0.4) | 0.18 |
| Geography | |||||
| GTHA§ | 156 804 (73.9) | 27 535 (63.4) | 125 380 (77.0) | 3889 (64.9) | < 0.001 |
| Ottawa | 9325 (4.4) | 1874 (4.3) | 7334 (4.5) | 117 (2.0) | < 0.001 |
Note: GTHA = Greater Toronto and Hamilton Area, ICU = intensive care unit, VOC = variant of concern.
↵* Unless indicated otherwise.
↵† p values based on χ2 test.
↵‡ Comorbidities include 1 or more of asthma, chronic obstructive pulmonary disease, hematological disease, liver disease, cardiac disease, diabetes, immune compromise, renal disease, neurologic disease, malignancy, or obesity.
↵§ Large conurbation in Central Ontario consisting of 6 health units (Toronto, Peel, Durham, Halton, York and Hamilton).