Secondary and safety outcomes, according to treatment arm
| Variable | No. (%) of patients* | IRR/OR/HR† | 95% CI | p value | |
|---|---|---|---|---|---|
| Intervention n = 217 | Control n = 212 | ||||
| GP consultations, median (IQR) | 15.0 (9.4 to 22.0) | 16.0 (10.0 to 22.0) | 0.93 | 0.79 to 1.10 | 0.40 |
| No. of patient weight measures, median (IQR) | 3 (1 to 5) | 3 (1 to 6) | 0.95 | 0.60 to 1.49 | 0.82 |
| At least 1 emergency consultation | 39 (18.0) | 45 (21.2) | 0.58 | 0.33 to 1.00 | 0.05 |
| At least 1 hospital admission | 62 (28.6) | 46 (21.7) | 1.00 | 0.65 to 1.53 | 1.00 |
| At least 1 stay in institution | 11 (5.1) | 10 (4.7) | 0.74 | 0.42 to 1.29 | 0.28 |
| At least 1 new chronic condition diagnosed‡ | 58 (28.9) | 57 (28.9) | 0.95 | 0.43 to 2.09 | 0.89 |
| Polymedication (> 4 drugs) at 2 yr | 115 (65.0) | 121 (66.1) | 0.94 | 0.59 to 1.50 | 0.80 |
| Potentially inappropriate medication§ | 133 (75.1) | 153 (83.6) | 0.60 | 0.30 to 1.19 | 0.14 |
| No. of specialists involved in care, median (IQR) | 2 (1 to 3) | 2 (1 to 3) | 0.90 | 0.72 to 1.13 | 0.36 |
| At least 1 contact by GP with home-based care | 54 (26.9) | 67 (34.0) | 0.70 | 0.43 to 1.14 | 0.15 |
| At least 1 contact by GP with family | 50 (24.9) | 43 (21.8) | 1.11 | 0.54 to 2.28 | 0.77 |
| Occurrence of any severe adverse event | 61 (28.1) | 67 (31.6) | 1.55 | 0.68 to 3.51 | 0.30 |
| Time to death or to admission to an institution | – | – | 1.43 | 0.76 to 2.72 | 0.27 |
Note: CI = confidence interval, GP = general practitioner, HR = hazard ratio, IQR = interquartile range, IRR = incidence rate ratio, OR = odds ratio.
↵* Unless indicated otherwise.
↵† IRRs are based on mixed negative binomial regression model, adjusted for cluster effect at GP level. ORs (for binary outcomes) are based on mixed logistic regression model, adjusted for cluster effect at GP level. HR is based on Cox survival analysis for time to death or admission to an institution.
↵‡ Based on a selection of codes from the International Classification for Primary Care, version 2.
↵§ Potentially inappropriate medication according to American Geriatrics Society 2015 updated Beers criteria.