Table 1:

Laboratory data for 60-year-old man with multisystem inflammatory syndrome after SARS-CoV-2 infection*

Laboratory valueOn admissionDay 1 after steroidsDay 2 after steroids, day 1 IVIGDay 3 steroids, day 2 IVIG, discharge day6 wk after discharge12 wk after discharge16 wk after dischargeReference range
Hematology and chemistry
C-reactive protein (mg/L)274.771.635.1< 0.6<–8.0
Ferritin (ug/L)8887317151548258300–500
D dimer (mg/LFEU)< 0.50
Leukocytes (109/L)–11.0
Neutrophils (109/L)14.013.316.–8.0
Platelet count (109/L)248375505464202218179150–400
Lymphocytes (109/L)–3.5
Hemoglobin (g/L)133125120116154151156137–180
Mean corpuscular vol. (fL)93929393969682–100
Triglycerides (mmol/L)2.111.651.501.670.00–1.70
ALT (U/L)4114988–40
Creatinine level (μmol/L)9778848278737450–120
Troponin (ng/L)380–13
NT-pro BNT (ng/L)28407063< 500–300
Lactate (mmol/L)2.20.5–2.2
Creatine kinase (U/L)290–195
Lipase (U/L)170–80
Lactate dehydrogenase (U/L)199100–235
Alkaline phosphatase (U/L)12830–145
Bilirubin total (μmol/L)150–24
Glucose (random) (mmol/L)7.13.3–11.0
Urine analysis
Epithelial cellsModerate/hpf
Hyaline cast5–10/lpf
Microbiology data
Blood culturesNegative × 2Negative
Urine cultureNegativeNegative
COVID-19 NATNegative and positive**NegativeNegative
COVID-19 serologyPositiveNegative
Respiratory infection panel§NegativeNegative
HIV serologyNegativeNegative
Hepatitis C antibodyNegativeNegative
  • Note: ALT = alanine aminotransferase, FEU = fibrinogen-equivalent units, hpf = high power field, INR = international normalized ratio, IVIG = intravenous immunoglobulin, lpf = low power field, NAT = nucleic acid amplification, NT pro-BNP = N-terminal pro–brain-type natriuretic peptide.

  • * Bolded values show abnormal results.

  • All COVID-19 NAT were on nasopharyngeal swabs.

  • Immunoglobulin G serology testing.

  • § Respiratory infection panel tests for influenza (A and B), parainfluenza virus (1, 2, 3, 4), human coronaviruses (229E, NL63, OC43, HKU1), metapneumovirus, enterovirus, rhinovirus and adenovirus.

  • No reference range, as normally not seen.

  • ** The patient had testing done as an outpatient on the day of admission (negative results) and then again when he went to the emergency department (positive results). For the positive nasopharyngeal swab, the cycle threshold value was 36 (very high), and insufficient for sequencing the spike protein and whole-genome sequencing. A higher cycle threshold value correlates with lower viral load1 and the repeat nasopharyngeal swab the next day came back negative. This likely suggests that the positive result was from residual RNA from the previous SARS-CoV-2 infection 4 weeks earlier, rather than reinfection or persistent infection.