Baseline characteristic | No. of patients (%)* | p value | |
---|---|---|---|
Discharged from hospital alive n = 49 | Died in hospital n = 121 | ||
Age, yr; median (P25, P75) | 61.5 (32, 69) | 64 (24, 70) | 0.3 |
Male sex | 16 (32.7) | 77 (63.6) | < 0.001 |
Onset of illness,† d; median (P25, P75) | 11 (6.5, 11.5) | 11 (7, 15) | 0.6 |
Presenting symptom | |||
Fever | 41 (83.7) | 101 (71.1) | 1.0 |
Cough | 30 (61.2) | 76 (62.8) | 0.9 |
Sputum | 8 (16.3) | 15 (12.4) | 0.6 |
Dyspnea | 15(30.6) | 62 (51.2) | 0.02 |
Diarrhea | 12 (24.5) | 25 (20.7) | 0.7 |
Chest pain | 3 (6.2) | 11 (9.1) | 0.8 |
Medical history | |||
Pre-existing CHD | 9 (18.4) | 21 (17.4) | 1.0 |
Hypertension | 30 (65.2) | 65 (53.7) | 0.2 |
Diabetes | 12 (24.5) | 25 (20.7) | 0.7 |
Stroke | 1 (2.0) | 5 (4.1) | 0.7 |
CKD | 4 (8.2) | 5 (4.1) | 0.3 |
Malignant disease | 2 (4.1) | 9 (7.4) | 0.5 |
COPD | 1 (2.0) | 10 (8.3) | 0.2 |
SOFA score on admission‡ | 4 (2.5, 5) | 4 (3, 5.25) | 0.3 |
APACHE II score on admission‡ | 10 (7, 15) | 11.5 (9, 16) | 0.4 |
Note: APACHE II = Acute Physiology and Chronic Health Evaluation score, CHD = coronary heart disease, CKD = chronic kidney disease, COPD = chronic obstructive pulmonary disease, COVID-19 = coronavirus disease 2019, P25 = 25th percentile, P75 = 75th percentile, SOFA = Sequential Organ Failure Assessment score.
↵* Unless otherwise defined.
↵† We defined the onset of illness as the onset of typical symptoms related to COVID-19, such as fever, dry cough and dyspnea.
↵‡ The SOFA and APACHE II scores were used to assess organ dysfunction and disease severity. Higher scores indicate a higher rate of organ failure and mortality. We calculated these scores from the data of only 64 patients.