Table 1:

Baseline characteristics of patients admitted to hospital with coronavirus disease 2019 who had elevated levels of cardiac troponin I

Baseline characteristicNo. of patients (%)*p value
Discharged from hospital alive
n = 49
Died in hospital
n = 121
Age, yr; median (P25, P75)61.5 (32, 69)64 (24, 70)0.3
Male sex16 (32.7)77 (63.6)< 0.001
Onset of illness, d; median (P25, P75)11 (6.5, 11.5)11 (7, 15)0.6
Presenting symptom
 Fever41 (83.7)101 (71.1)1.0
 Cough30 (61.2)76 (62.8)0.9
 Sputum8 (16.3)15 (12.4)0.6
 Dyspnea15(30.6)62 (51.2)0.02
 Diarrhea12 (24.5)25 (20.7)0.7
 Chest pain3 (6.2)11 (9.1)0.8
Medical history
 Pre-existing CHD9 (18.4)21 (17.4)1.0
 Hypertension30 (65.2)65 (53.7)0.2
 Diabetes12 (24.5)25 (20.7)0.7
 Stroke1 (2.0)5 (4.1)0.7
 CKD4 (8.2)5 (4.1)0.3
 Malignant disease2 (4.1)9 (7.4)0.5
 COPD1 (2.0)10 (8.3)0.2
 SOFA score on admission4 (2.5, 5)4 (3, 5.25)0.3
 APACHE II score on admission10 (7, 15)11.5 (9, 16)0.4
  • Note: APACHE II = Acute Physiology and Chronic Health Evaluation score, CHD = coronary heart disease, CKD = chronic kidney disease, COPD = chronic obstructive pulmonary disease, COVID-19 = coronavirus disease 2019, P25 = 25th percentile, P75 = 75th percentile, SOFA = Sequential Organ Failure Assessment score.

  • * Unless otherwise defined.

  • We defined the onset of illness as the onset of typical symptoms related to COVID-19, such as fever, dry cough and dyspnea.

  • The SOFA and APACHE II scores were used to assess organ dysfunction and disease severity. Higher scores indicate a higher rate of organ failure and mortality. We calculated these scores from the data of only 64 patients.