Initiation of thyroid hormone therapy during pregnancy and continued after delivery in relation to first and highest TSH values
| Variable | First or highest TSH value (mIU/L); no. (%) of deliveries* | |||||
|---|---|---|---|---|---|---|
| < 0.10 | 0.10–2.50 | 2.51–4.00 | 4.01–9.99 | ≥ 10.00 | All | |
| By first TSH value during pregnancy | n = 1780 | n = 88 534 | n = 15 082 | n = 4417 | n = 1709 | n = 111 522 |
| Initiated on thyroid hormone | 29 (1.6) | 750 (0.8) | 1520 (10.1) | 2451 (55.5) | 300 (17.6) | 5050 (4.5) |
| Continued on thyroid hormone after delivery | 10 (34.5) | 357 (47.6) | 499 (32.8) | 1175 (47.9) | 211 (70.1) | 2252 (44.6) |
| Continued on thyroid hormone after delivery with ≥ 2 prescriptions in first year† | 8 (27.6) | 256 (34.1) | 314 (20.7) | 844 (34.4) | 169 (56.3) | 1591 (31.5) |
| By highest TSH value during pregnancy | n = 591 | n = 87 835 | n = 16 141 | n = 4953 | n = 2002 | n = 111 522 |
| Initiated on thyroid hormone | n < 5 | 532 (0.6) | 1371 (8.5) | 2783 (56.2) | 362 (18.1) | 5050 (4.5) |
| Continued on thyroid hormone after delivery | 0 (0) | 265 (49.8) | 426 (31.1) | 1312 (47.1) | 249 (68.8) | 2252 (44.6) |
| Continued on thyroid hormone after delivery with ≥ 2 prescriptions in first year† | 0 (0) | 191 (35.9) | 270 (19.7) | 932 (33.5) | 198 (54.7) | 1591 (31.5) |
Note: TSH = thyroid-stimulating hormone.
↵* The denominator for calculating each percentage is the n value in the previous row (same column), unless otherwise indicated.
↵† The denominator for calculating each percentage in this row is the count of pregnancies with initiation of thyroid hormone therapy during the pregnancy (same column).