Table 1:

Baseline characteristics of participants from the Copenhagen General Population Study,17 by blood lymphocyte count

CharacteristicNo. (%) of participants*
Participants with lymphopenia (lymphocyte count < 1.1 × 109/L)
n = 2647
Reference group (lymphocyte count = 1.1–3.7 × 109/L)
n = 102 879
Participants with lymphocytosis (lymphocyte count > 3.7 × 109/L)
n = 2610
Blood lymphocyte count, × 109/L; median (IQR)1.0 (0.1–1.09)2.1 (1.1–3.69)4.0 (3.7–125)
Age, yr; median (IQR)68 (58–77)58 (48–67)58 (48–66)
Male sex1465 (55)46 145 (45)986 (38)
Ever smoked1529 (58)59 102 (57)1951 (75)
Cumulative smoking, pack-years; median (IQR)16 (5–32)15 (6–30)25 (13–40)
Alcohol consumption > 168 g/wk for men, > 84 g/wk for women1081 (41)40 261 (39)938 (36)
Body mass index, kg/m2; median (IQR)25 (23–28)26 (23–28)27 (24–30)
Plasma C-reactive protein, mg/L; median (IQR)1.6 (1.0–3.4)1.4 (0.9–2.2)1.8 (1.2–3.4)
Blood neutrophil count, × 109/L; median (IQR)3.7 (2.9–4.8)4.0 (3.3–4.9)5.0 (4.1–6.1)
Any recent infection136 (5)3969 (4)139 (5)
Diabetes164 (6)3717 (4)125 (5)
Systolic blood pressure, mm Hg; median (IQR)142 (128–158)140 (126–155)141 (128–158)
Plasma cholesterol, mmol/L; median (IQR)5.3 (4.5–6.0)5.5 (4.8–6.3)5.8 (5.1–6.5)
Plasma triglycerides, mmol/L; median (IQR)1.2 (0.9–1.8)1.4 (0.9–2.0)1.8 (1.2–2.7)
High income§1288 (49)65 389 (64)1499 (57)
High leisure-time physical activity1257 (48)53 066 (52)1053 (40)
More than 12 years of education2063 (78)81 132 (79)1842 (71)
Comorbidity**2095 (79)55 635 (54)1819 (70)
  • Note: IQR = interquartile range.

  • * Unless specified otherwise.

  • Only ever smokers.

  • Values from the The Danish State Health Authority (latest national recommendations available at www.sst.dk/da/Udgivelser/2018/Forebyggelsespakke-Alkohol [in Danish]).

  • § Greater than or equal to 400 000 Danish krone/household.

  • More than 4 hours of physical activity a week.

  • ** Defined as participants with any comorbidity or with routine blood test results outside the reference range.