Association between type of maternal prepregnancy surgery and risk of neonatal abstinence syndrome in infants Type of surgery* No. of infants
| Type of surgery* | No. of infants | No. of infants with neonatal abstinence syndrome | Prevalence per 10 000 (95% CI) | Risk ratio (95% CI) | |
|---|---|---|---|---|---|
| Unadjusted | Adjusted† | ||||
| General | 182 550 | 298 | 16.3 (14.5–18.2) | 1.86 (1.63–2.12) | 1.72 (1.51–1.97) |
| Cardiovascular or thoracic | 5317 | 23 | 43.3 (25.6–60.9) | 4.99 (3.23–7.72) | 4.45 (2.87–6.91) |
| Neurosurgery | 3858 | 12 | 31.1 (13.5–48.7) | 3.69 (1.96–6.96) | 3.00 (1.56–5.77) |
| Orthopedic | 76 187 | 138 | 18.1 (15.1–21.1) | 2.10 (1.75–2.53) | 1.98 (1.60–2.46) |
| Urologic | 12 355 | 42 | 34.0 (23.7–44.3) | 3.85 (2.81–5.27) | 3.03 (2.16–4.26) |
| Obstetric or gynecologic | 321 806 | 541 | 16.8 (15.4–18.2) | 1.88 (1.69–2.09) | 1.80 (1.61–2.02) |
| Plastic or dermatologic | 72 001 | 130 | 18.1 (15.0–21.2) | 2.06 (1.70–2.49) | 2.13 (1.76–2.58) |
| Ophthalmology | 11 630 | 23 | 19.8 (11.7–27.9) | 2.26 (1.43–3.57) | 2.44 (1.54–3.86) |
| Otorhinolaryngology | 140 653 | 235 | 16.7 (14.6–18.8) | 1.89 (1.64–2.19) | 1.95 (1.68–2.25) |
| Oral and maxillofacial or dental | 48 874 | 92 | 18.8 (15.0–22.7) | 2.17 (1.73–2.70) | 2.15 (1.73–2.68) |
| Other | 9062 | 16 | 17.7 (9.0–26.3) | 1.91 (1.13–3.22) | 1.52 (0.90–2.54) |
| No surgery | 1 476 399 | 1294 | 8.8 (8.3–9.2) | Referent | Referent |