Prevalence of neonatal abstinence syndrome in newborns according to maternal characteristics
| Characteristics | No. of infants | No. of infants with neonatal abstinence syndrome | Prevalence per 10 000 (95% CI) |
|---|---|---|---|
| Prepregnancy surgery | |||
| Yes | 705 966 | 1052 | 14.9 (14.0–15.8) |
| No | 1 476 399 | 1294 | 8.8 (8.3–9.2) |
| Maternal pain comorbidity* | |||
| Yes | 148 769 | 265 | 17.8 (15.7–20.0) |
| No | 2 033 596 | 2081 | 10.2 (9.8–10.7) |
| Maternal mental illness† | |||
| Yes | 35 666 | 249 | 69.8 (61.2–78.5) |
| No | 2 146 699 | 2097 | 9.8 (9.4–10.2) |
| Maternal age at delivery, yr | |||
| < 25 | 455 057 | 801 | 17.6 (16.4–18.8) |
| 25–34 | 1 429 257 | 1290 | 9.0 (8.5–9.5) |
| ≥ 35 | 298 051 | 255 | 8.6 (7.5–9.6) |
| Parity | |||
| 0 | 1 230 909 | 1282 | 10.4 (9.8–11.0) |
| 1 | 696 558 | 581 | 8.3 (7.7–9.0) |
| ≥ 2 | 254 898 | 483 | 18.9 (17.3–20.6) |
| Socioeconomic deprivation | |||
| Yes | 432 410 | 805 | 18.6 (17.3–19.9) |
| No | 1 638 542 | 1431 | 8.7 (8.3–9.2) |
| Place of residence | |||
| Rural | 419 754 | 400 | 9.5 (8.6–10.5) |
| Urban | 1 704 423 | 1925 | 11.3 (10.8–11.8) |
| Time period | |||
| 1989–2005 | 1 351 672 | 1417 | 10.5 (9.9–11.0) |
| 2006–2016 | 830 693 | 929 | 11.2 (10.5–11.9) |
| Total | 2 182 365 | 2346 | 10.7 (10.3–11.2) |
Note: CI = confidence interval.
↵* Cancer, neuropathy, migraine and other headaches, dorsopathy, musculoskeletal disorders, arthropathy, urolithiasis, reproductive disorders, inflammatory bowel disease and sickle cell disease.
↵† Depression, bipolar disorder, schizophrenia, anxiety disorder, stress-related disorder, personality disorder and suicide attempt.