Absolute rate of venous thromboembolism per 10 000 person-years and hazard ratios
| Variable | Control patients | Patients with gout | Unadjusted HR (95% CI) | Adjusted HR* (95% CI) | ||||
|---|---|---|---|---|---|---|---|---|
| N | Person-years | Rate (95% CI) | N | Person-years | Rate (95% CI) | |||
| Overall | 1071 | 396 095 | 27.0 (25.5–28.9) | 1481 | 396 990 | 37.3 (35.5–39.3) | 1.38 (1.28–1.49) | 1.25 (1.15–1.35) |
| Gender | ||||||||
| Male | 721 | 297 075 | 24.3 (22.6–26.1) | 953 | 298 577 | 31.9 (30.0–34.0) | 1.31 (1.19–1.45) | 1.20 (1.09–1.33) |
| Female | 350 | 99 020 | 35.3 (31.8–39.3) | 528 | 98 413 | 53.7 (49.3–58.4) | 1.52 (1.33–1.74) | 1.32 (1.14–1.52) |
| Age, yr | ||||||||
| < 50 | 63 | 97 437 | 6.5 (5.1–8.3) | 126 | 97 224 | 13.0 (10.9–15.4) | 2.00 (1.48–2.71) | 1.79 (1.30–2.48) |
| 50–59 | 140 | 86 944 | 16.1 (13.6–19.0) | 214 | 86 633 | 24.7 (21.6–28.2) | 1.53 (1.24–1.90) | 1.40 (1.12–1.75) |
| 60–69 | 269 | 93 635 | 28.7 (25.5–32.4) | 393 | 93 734 | 41.9 (38.0–46.3) | 1.46 (1.25–1.70) | 1.25 (1.06–1.47) |
| 70–79 | 377 | 81 384 | 46.3 (41.9–51.2) | 482 | 82 440 | 58.5 (53.5–63.9) | 1.26 (1.10–1.44) | 1.18 (1.02–1.36) |
| > 80 | 222 | 36 694 | 60.5 (53.0–69.0) | 266 | 36 960 | 72.0 (63.8–81.2) | 1.19 (0.99–1.42) | 1.16 (0.96–1.39) |
| Deprivation index quintiles | ||||||||
| 1 (least deprived) | 251 | 101 402 | 24.8 (21.9–28.0) | 345 | 99 888 | 34.5 (31.0–38.4) | 1.40 (1.19–1.64) | 1.31 (1.10–1.54) |
| 2 | 271 | 99 615 | 27.2 (24.2–30.6) | 360 | 99 706 | 36.1 (32.6–40.0) | 1.33 (1.13–1.55) | 1.22 (1.03–1.44) |
| 3 | 213 | 79 824 | 26.7 (23.3–30.5) | 308 | 80 398 | 38.3 (34.3–42.8) | 1.44 (1.21–1.71) | 1.28 (1.06–1.53) |
| 4 | 192 | 66 674 | 28.8 (25.0–33.2) | 283 | 67 770 | 41.8 (37.2–47.0) | 1.45 (1.20–1.74) | 1.29 (1.07–1.57) |
| 5 (most deprived) | 143 | 48 219 | 30.0 (25.2–35.0) | 183 | 48 879 | 37.4 (32.4–43.3) | 1.26 (1.01–1.57) | 1.09 (0.87–1.37) |
Note: CI = confidence interval, HR = hazard ratio.
↵* Adjusted for age, gender, Charlson index calendar year, smoking status, hospital admission, deprivation, hypertension, diabetes, acetylsalicylic acid use, thiazide use, alcohol consumption and body mass index.