Absolute and relative rate of venous thromboembolism by hospital admission and time after gout diagnosis
| Variable | Control patients | Patients with gout | IRR (95% CI) | IRR (95% CI) adjusted* | ||||
|---|---|---|---|---|---|---|---|---|
| N | Person-years | Rate (95% CI) | N | Person-years | Rate (95% CI) | |||
| Hospital admission | ||||||||
| In-hospital period | 178 | 2145 | 829.8 (716.3–961.1) | 230 | 2787 | 825.2 (725.1–939.0) | 0.99 (0.82–1.21) | 1.01 (0.83–1.24) |
| Ambulatory period | 893 | 393 950 | 22.7 (21.2–24.2) | 1251 | 394 203 | 31.7 (30.0–33.5) | 1.40 (1.28–1.53) | 1.30 (1.18–1.42) |
| Before hospital admission | 439 | 306 627 | 14.3 (13.0–15.7) | 574 | 283 368 | 20.3 (18.7–22.0) | 1.41 (1.25–1.60) | 1.37 (1.19–1.56) |
| Postdischarge period | 454 | 87 323 | 52.0 (47.4–57.0) | 677 | 110 835 | 61.1 (56.5–65.9) | 1.17 (1.04–1.32) | 1.15 (1.02–1.31) |
| Time after gout diagnosis in years | ||||||||
| 1 | 119 | 62 179 | 19.1 (16.0–22.9) | 208 | 62 134 | 33.5 (29.2–38.4) | 1.75 (1.40–2.19) | 1.70 (1.35–2.16) |
| > 1–6 | 611 | 221 787 | 27.5 (25.5–29.8) | 817 | 222 456 | 36.7 (34.3–39.3) | 1.33 (1.20–1.48) | 1.22 (1.10–1.37) |
| > 6–10 | 231 | 79 517 | 29.1 (25.5–33.1) | 320 | 79 826 | 46.1 (35.9–44.7) | 1.38 (1.17–1.63) | 1.28 (1.06–1.52) |
| > 10 | 110 | 32 613 | 33.7 (28.0–40.7) | 136 | 32 574 | 41.7 (35.3–49.4) | 1.24 (0.96–1.59) | 1.06 (0.81–1.38) |
Note: CI = confidence interval, IRR = incidence rate ratio
↵* Adjusted for age, gender, Charlson index calendar year, smoking status, hospital admission, deprivation, hypertension, diabetes, acetylsalicylic acid use, thiazide use, alcohol consumption and body mass index.