Table 3:

Association between statin dose and 1-year admission to hospital for cardiovascular events in older Ontario residents living in long-term care facilities who were prescribed statins, overall and by subgroup*

AnalysisNo. of matched pairs analyzedOne-year cumulative incidence of admission to hospital for cardiovascular events, %Risk difference in 1-yr cumulative incidence, % (95% CI)HR (95% CI)
Residents taking intensive-dose statinsResidents taking moderate-dose statins
Primary analysis, all matched pairs457711.4111.45−0.04 (−1.34 to 1.26)0.99 (0.88 to 1.12)
Stratified analysis
Sex
 Female277610.3410.77−0.43 (−2.05 to 1.19)0.96 (0.82 to 1.12)
 Male180113.0512.490.56 (−1.62 to 2.74)1.04 (0.87 to 1.25)
History of atherosclerotic-related admission to hospital
 No15608.088.21−0.13 (−2.06 to 1.80)0.98 (0.77 to 1.25)
 Yes301713.1313.130.00 (−1.69 to 1.69)1.00 (0.87 to 1.15)
Frailty status
 Prefrail or not frail211912.1312.41−0.28 (−2.26 to 1.70)0.98 (0.82 to 1.16)
 Frail245810.7810.620.16 (−1.57 to 1.89)1.01 (0.85 to 1.20)
  • Note: CI = confidence interval, HR = hazard ratio.

  • * Statins prescribed between Apr. 1, 2013, and Mar. 31, 2014.

  • Residents taking moderate-dose statins served as the reference category.