Age of women at initial screen, yr | Years after screening | Breast cancers estimated as overdiagnosed, % | |
---|---|---|---|
Invasive and in situ cancers, % | Invasive cancers, % | ||
40 to 49 | 5 | 41 | 32 |
20 | 55 | 48 | |
50 to 59 | 5 | 25 | 16 |
20 | 16 | 5 |
↵* Overdiagnosis by age was estimated using this calculation: The numerator is the difference in numbers of cancers in the mammography arm less those in the control arm; and the denominator is the number of screen-detected cancers in the mammography arm. (39) Only the findings from the estimate on overdiagnosis from a Canadian randomized controlled trial (39) are included because it provided an estimate by age and was appraised as being at moderate risk of bias. (15)