Characteristic | No. (%) of patients* | p value | Absolute standardized difference | |
---|---|---|---|---|
Women n = 42 746 | Men n = 47 961 | |||
Age at diagnosis, yr, mean ± SD | 75.8 ± 12.9 | 71.5 ± 12.8 | < 0.001 | 0.33 |
Rural residence | 5358 (12.5) | 6788 (14.2) | < 0.001 | 0.05 |
Income quintile† | ||||
1 (lowest) | 9613 (22.5) | 9541 (19.9) | < 0.001 | 0.06 |
2 | 9243 (21.6) | 9833 (20.5) | 0.03 | |
3 | 8325 (19.5) | 9444 (19.7) | 0.01 | |
4 | 8017 (18.8) | 9775 (20.4) | 0.04 | |
5 (highest) | 7388 (17.3) | 9188 (19.2) | 0.05 | |
Comorbidities | ||||
Benign hypertension | 32 809 (76.8) | 34 103 (71.1) | < 0.001 | 0.13 |
Complicated hypertension | 5669 (13.3) | 6516 (13.6) | 0.2 | 0.01 |
Atrial fibrillation | 5957 (13.9) | 6919 (14.4) | 0.04 | 0.01 |
Myocardial infarction | 5051 (11.8) | 9617 (20.1) | < 0.001 | 0.23 |
Valvular disease | 2099 (4.9) | 2841 (5.9) | < 0.001 | 0.04 |
Peripheral arterial disease | 1272 (3.0) | 2257 (4.7) | < 0.001 | 0.09 |
Cerebrovascular disease | 2506 (5.9) | 2713 (5.7) | 0.2 | 0.01 |
Pulmonary circulatory disease | 1113 (2.6) | 882 (1.8) | < 0.001 | 0.05 |
COPD or asthma | 16 261 (38.0) | 17 164 (35.8) | < 0.001 | 0.05 |
Alcohol abuse | 337 (0.8) | 1123 (2.3) | < 0.001 | 0.13 |
Renal disease | 1954 (4.6) | 2865 (6.0) | < 0.001 | 0.06 |
Diabetes | 14 751 (34.5) | 18 721 (39.0) | < 0.001 | 0.09 |
Hypothyroidism | 1300 (3.0) | 479 (1.0) | < 0.001 | 0.15 |
Liver disease | 579 (1.4) | 895 (1.9) | < 0.001 | 0.04 |
Dementia | 1791 (4.2) | 1194 (2.5) | < 0.001 | 0.09 |
Depression | 1213 (2.8) | 756 (1.6) | < 0.001 | 0.09 |
Psychosis | 223 (0.5) | 171 (0.4) | < 0.001 | 0.02 |
Primary tumour | 3376 (7.9) | 4419 (9.2) | < 0.001 | 0.05 |
Metastatic cancer | 1000 (2.3) | 840 (1.8) | < 0.001 | 0.04 |
Paraplegia | 434 (1.0) | 475 (1.0) | 0.7 | 0.003 |
Venous thromboembolism | 450 (1.1) | 512 (1.1) | 0.8 | 0.001 |
Frailty | 11 223 (26.3) | 8409 (17.5) | < 0.001 | 0.21 |