Table 5:

Comparison of the cognitive quotient method and the Mini-Mental State Examination cut-off method for identifying participants with dementia, by sample population*

ParameterQuoCoMMSE < 24
CSHA participantsNACC participantsCSHA participantsNACC participants
Sensitivity (95% CI)80 (77 to 83)68 (63 to 72)74 (71 to 77)47 (42 to 51)
Specificity (95% CI)82 (81 to 84)90 (90 to 91)92 (91 to 93)99 (99 to 99)
PPV (95% CI)44 (42 to 47)37 (34 to 40)63 (60 to 66)80 (75 to 84)
NPV (95% CI)96 (95 to 96)97 (97 to 98)95 (95 to 96)96 (95 to 96)
LR+4.446.809.2547
LR−0.240.360.280.54
  • Note: CSHA = Canadian Study of Health and Aging, (22) LR+ = positive likelihood ratio, LR− = negative likelihood ratio, MMSE = Mini-Mental State Examination, NACC = National Alzheimer’s Coordinating Center’s Uniform Data Set, (25) NPV = negative predictive value, PPV = positive predictive value, QuoCo = cognitive quotient.

  • * Reported values are for participants who completed at least 2 visits.