Test | Baseline | Week 2 | Week 12 |
---|---|---|---|
HIV testing* | X | X† | |
Hepatitis A immunity (hepatitis A total antibody)‡ | X | ||
Hepatitis B screen‡§ (surface antigen, surface antibody, core antibody) | X | ||
Hepatitis C screen (hepatitis C antibody) | X | X | |
Screening for gonorrhea and chlamydia¶ (urine nucleic acid amplification test; throat and rectal swabs for culture or nucleic acid amplification; test anatomic sites depending on type of sexual activity reported) | X | X | |
Syphilis serology¶ | X | X | |
Complete blood count | X | ||
Alanine aminotransferase | X | X** | |
Serum creatinine | X | X** | |
Pregnancy testing (if appropriate) | X |
↵* Preferred HIV test is a 4th-generation antibody/antigen combo assay. Those with signs or symptoms of acute HIV should also undergo HIV RNA or pooled nucleic acid amplification test.
↵† Consider repeating HIV serology at 6 months after exposure if hepatitis C infection was acquired from the exposure.
↵‡ Hepatitis A and/or B vaccine should be started in unvaccinated individuals.
↵§ Individuals with chronic active hepatitis B should be referred for hepatitis B virus care as per local guidelines.
↵¶ Individuals diagnosed with concurrent sexually transmitted infection during nonoccupational postexposure prophylaxis should be offered standard therapy and follow-up as per local guidelines.
↵** Suggested if abnormal at baseline or symptomatic.