Table 3:

Survival analyses of the mortality risk associated with current depression among men and women in the Stirling County Study by time period, 1952–2011 (n = 3410)*

Survival modelMen, HR (95% CI)Women, HR (95% CI)
1952–19671968–19901991–20111952–19671968–19901991–2011
Mortality risk associated with depression at the most recent interview,2.90 (1.69–4.98)1.97 (1.34–2.89)1.52 (1.09–2.13)1.08 (0.53–2.22)1.37 (0.90–2.07)1.51 (1.11–2.05)
Mortality risk adjusted for education, smoking, alcohol abuse and obesity2.84 (1.59–5.07)2.00 (1.34–2.98)1.32 (0.93–1.87)1.10 (0.53–2.26)1.33 (0.86–2.05)1.62 (1.19–2.21)
No. of deaths122440476111347569
Person-years7093.915 360.013 994.39848.818 858.018 466.9
  • Note: CI = confidence interval, HR = hazard ratio.

  • * These analyses combine person-time contributed from all 3 Stirling County Study samples together, thereby allowing for robust estimation of secular trends. Using data from the follow-up interviews allowed us to shorten considerably the time from last assessment of depression status: 64% of the combined sample had their depression status assessed less than 20 years ago compared with 21% when only depression at baseline was considered.

  • Test of the 3-way interactions between gender*calendar period*depression status at recent interview: χ2 = 3.81, df = 2, p = 0.2.

  • Test of interaction between depression at the most recent interview and sample: χ2 = 1.26, df = 2, p = 0.5 for men, and χ2 = 1.23, df = 2, p = 0.5 for women.