Medication | Medication added to treatment | p value | |
---|---|---|---|
Patients with peridiagnostic pulmonary function testing, % | Patients without peridiagnostic pulmonary function testing, % | ||
Overall | |||
Long-acting anticholinergic | 44.5 | 25.4 | < 0.001 |
Long-acting β agonist | 3.0 | 1.8 | < 0.001 |
Long-acting β agonist and inhaled corticosteroid combination | 30.1 | 18.7 | < 0.001 |
Inhaled corticosteroid | 13.6 | 12.5 | 0.04 |
COPD diagnosed in the ambulatory care setting | |||
Long-acting anticholinergic | 44.1 | 21.0 | < 0.001 |
Long-acting β agonist | 2.7 | 1.1 | < 0.001 |
Long-acting β agonist and inhaled corticosteroid combination | 28.6 | 16.9 | < 0.001 |
Inhaled corticosteroid | 12.5 | 10.7 | 0.01 |
COPD diagnosed in the hospital setting | |||
Long-acting anticholinergic | 44.9 | 30.5 | < 0.001 |
Long-acting β agonist | 3.3 | 2.8 | 0.2 |
Long-acting β agonist and inhaled corticosteroid combination | 31.8 | 20.9 | < 0.001 |
Inhaled corticosteroid | 14.9 | 14.7 | 0.8 |
Note: COPD = chronic obstructive pulmonary disease.
↵* A medication was considered to be newly added to a patient’s treatment if there were no prescriptions for the medication in the year before the pulmonary function test date or its equivalent, and at least 1 prescription for it in the year after the pulmonary function test date.
↵† For patients with pulmonary function testing (cases), the pulmonary function test date was the date on which they received their pulmonary function test. For patients without pulmonary function testing (controls), the pulmonary function test equivalent date was determined by calculating the number of days between the pulmonary function test and the index date of their matched case and then counting back that number of days from their index date.