Table 4:

Prognostic factors in Parkinson disease57

Predictors of a more benign coursePredictors of a more rapid course
  • Early onset24

  • Tremor-predominant

  • Female sex118

  • Late onset24

  • Male sex118

  • Postural instability (predominant gait difficulty)

  • Rigidity or bradykinesia as first symptom

  • Dementia

  • Poor response to levodopa

  • Associated comorbidities (e.g., stroke)