Clinical presentation of selected non–IgE mediated, and mixed IgE- and non–IgE-mediated food allergies6
| Disorder | Clinical features |
|---|---|
| Food protein-induced enterocolitis (non–IgE-mediated) | Severe vomiting, lethargy, possible hypotension or cyanosis, with symptom onset two hours after ingestion; common triggers are milk, soy, rice and oats |
| Food protein-induced proctocolitis (non–IgE-mediated) | Bloody stools in an otherwise healthy infant; typically occurs in breastfed infants and is most often related to maternal ingestion of cow’s milk |
| Eosinophilic esophagitis (mixed IgE and non-IgE mediated) | Aversion to feeding in infants, abdominal pain, dysphagia, esophageal food impaction |