Table 1:

Recorded medications for depression in patients with diagnoses of both Parkinson disease and depression in the Canadian Primary Care Sentinel Surveillance Network

CharacteristicOverall, no. (%)*
n = 578
Type of medication for depression
 Selective serotonin reuptake inhibitors302 (52.2)
 Benzodiazepines and related hypnosedatives273 (47.2)
 Atypical antipsychotic agents183 (31.7)
 Serotonin–norepinephrine reuptake inhibitors99 (17.1)
 Serotonin antagonist and reuptake inhibitors75 (13.0)
 Tricyclics and tetracyclics57 (9.9)
 Amitriptyline26 (4.5)
 Bipolar medications54 (9.3)
 Monoamine oxidase inhibitors9 (1.6)
 No depression medication(80) 13.8
  • * Unless otherwise specified.

  • Tricyclic recommended in Canadian guidelines on Parkinson disease.12