Diagnostic accuracy of different cut-off points of absolute high-sensitivity cardiac troponin T levels at baseline and changes within the first hour
| Cut-off point, ng/L | % (95% CI) | |||
|---|---|---|---|---|
| Sensitivity | Specificity | Positive predictive value | Negative predictive value | |
| Baseline | ||||
| 5 | 99.6 (97.6–100.0) | 37.9 (35.0–40.9) | 25.4 (22.6–28.4) | 99.8 (98.7–100.0) |
| 10 | 94.4 (90.6–97.0) | 70.0 (67.2–72.7) | 40.0 (35.9–44.2) | 98.3 (97.1–99.1) |
| 14 | 92.1 (88.4–95.3) | 79.4 (76.3–81.3) | 48.4 (43.3–53.3) | 98.1 (96.5–98.6) |
| 20 | 80.1 (74.3–85.0) | 89.0 (87.0–90.8) | 60.7 (54.9–66.2) | 95.5 (94.0–96.7) |
| 50 | 50.2 (43.6–56.8) | 97.6 (96.5–98.4) | 81.7 (74.3–87.7) | 90.2 (88.4–91.9) |
| 100 | 29.0 (23.2–35.3) | 99.3 (98.6–99.7) | 89.3 (80.0–95.3) | 86.8 (84.8–88.7) |
| Within 1 hour | ||||
| 1 | 84.4 (79.1–88.8) | 84.9 (82.6–86.9) | 54.2 (48.9–59.4) | 96.2 (94.8–97.4) |
| 3 | 70.1 (63.8–76.0) | 95.7 (94.3–96.8) | 77.5 (71.2–83.0) | 93.8 (92.2–95.1) |
| 5 | 59.3 (52.7–65.7) | 97.3 (96.1–98.1) | 82.0 (75.4–87.5) | 91.8 (90.1–93.4) |
| 10 | 42.4 (36.0–49.1) | 98.2 (97.2–98.9) | 83.1 (75.0–89.3) | 88.9 (87.0–90.7) |
| 15 | 35.9 (29.7–42.5) | 98.5 (97.6–99.2) | 83.8 (75.0–90.5) | 87.9 (85.9–89.7) |
| 25 | 25.5 (20.0–31.7) | 99.2 (98.4–99.6) | 86.8 (76.3–93.8) | 86.3 (84.2–88.1) |
Note: CI = confidence interval.