Association between diagnosis of polymyalgia rheumatica and all vascular events, by sex and age
| Characteristic | All vascular events, rate per 1000 person-years (95% CI) | Hazard ratio (95% CI) | ||
|---|---|---|---|---|
| PMR | No PMR | Unadjusted | Adjusted* | |
| Sex | ||||
| Male | 43.7 (38.9–49.3) | 15.7 (14.3–17.3) | 2.8 (2.4–3.2) | 2.5 (2.1–2.9) |
| Female | 33.5 (30.9–36.2) | 11.0 (10.3–11.8) | 3.1 (2.7–3.3) | 2.7 (2.4–2.9)† |
| Age, yr | ||||
| 50–59 | 19.5 (15.1–25.0) | 3.5 (2.6–4.6) | 5.6 (3.8–8.1) | 5.0 (3.4–7.4) |
| 60–69 | 27.6 (24.2–31.5) | 8.1 (7.2–9.1) | 3.4 (2.9–4.1) | 2.9 (2.4–3.5) |
| 70–79 | 40.1 (36.4–44.1) | 16.0 (14.9–17.3) | 2.5 (2.2–2.8) | 2.3 (2.1–2.7) |
| ≥ 80 | 56.9 (49.6–64.8) | 19.8 (17.6–22.3) | 2.8 (2.4–3.4) | 2.6 (2.1–3.1) |
Note: CI = confidence interval, PMR = polymyalgia rheumatia.
↵* Adjusted for age, sex, ever having smoked, and record of hypertension, hyperlipidemia, diabetes or giant cell arteritis. Models stratified by age were adjusted only for sex, and vice versa.
↵† Assuming separate baseline hazards for those with and without diabetes mellitus.