Table 2:

Outcomes at 6 months: intention-to-treat analysis

VariableNo. (%) or mean ± SDDifference (intervention – control), SD* (95% CI)
Pharmacist-led group
n = 143
Nurse-led group
n = 136
At guideline-recommended systolic blood pressure level at baseline91 (63.6)85 (62.5)1.1% (−10.8 to 13.1)
At guideline-recommended lipid level at baseline8 (5.6)7 (5.2)0.4% (−5.0 to 5.6)
Attained guideline-recommended systolic blood pressure level by 6 mo115 (80.4)122 (89.7)−9.3% (−17.0 to −0.2)
Attained guideline-recommended LDL level by 6 mo73 (51.1)46 (33.8)17.2% (4.9 to 29.0)
Primary outcome
Attained optimal systolic blood pressure and lipid level by 6 mo62 (43.4)42 (30.9)12.5% (0.4 to 24.0)
Secondary outcomes
Systolic blood pressure at 6 mo126.5 ± 17.9122.2 ± 13.04.3 (0.6 to 8.0)
LDL cholesterol at 6 mo2.21 ± 0.732.35 ± 0.81−0.14 (−0.32 to 0.04)
Change in systolic blood pressure over 6 mo−8.1 ± 16.0−11.4 ± 16.33.3 (0.5 to 7.1)
Change in LDL over 6 mo−0.98 ± 0.96−0.90 ± 0.90−0.7 (−0.30 to 0.16)
Mortality0 (0)1 (0.7)−0.7% (−0.7 to 0.6)
Vascular event9 (6.3)8 (5.9)0.4% (−5.4 to 6.0)
Change in HDL cholesterol−0.01 ± 0.23−0.04 ± 0.190.03 (−0.02 to 0.08)
Change in total:HDL ratio−1.13 ± 1.13−1.03 ± 1.07−0.10 (−0.36 to 0.16)
Self-reported adherence of 75% or higher for blood pressure or lipid-lowering medications138 (96.5)132 (97.1)−0.6% (−4.3 to 3.7)
Change in body mass index−0.20 ± 1.39−0.09 ± 3.3−0.11 (−0.70 to 0.48)
Current smokers at baseline who stopped during 6-mo period4/24 (16.7)6/16 (37.5)−20.8% (−46.9 to 10.5)
Overall self-rated health3.5 ± 0.93.4 ± 0.80.1 (−0.1 to 0.3)
EQ-5D index score0.84 ± 0.150.86 ± 0.17−0.02 (−0.06 to 0.02)
Overall rating of health care satisfaction4.35 ± 0.924.40 ± 0.79−0.05 (−0.25 to 0.15)
Physical activity meets Canadian guidelines§11 (10.1)6 (4.8)3.3% (−2.9 to 8.1)
  • Note: CI = confidence interval, EQ-5D = EuroQol Health Questionnaire, HDL = high-density lipoprotein, LDL = low-density lipoprotein, SD = standard deviation.

  • * Unless otherwise stated.

  • Myocardial infarction, stroke or transient ischemic attack, coronary or carotid revascularization.

  • Scored on a 5-point Likert scale with 5 being excellent and 1 being poor.

  • § Individuals reporting at least 120 minutes of moderate or strenuous physical activity per week.