Characteristics of the included patients, by time from the onset of symptoms to percutaneous coronary intervention and the presence of baseline Q waves
| Characteristic; median (25th, 75th percentile)* | All patients n = 4341 | Time from the onset of symptoms to PCI | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤ 3 h n = 1052 | > 3 to ≤ 6 h n = 1675 | > 6 hr n = 1614 | ||||||||||
| No Q waves n = 2338 | Q waves n = 2003 | p value | No Q waves n = 631 | Q waves n = 421 | p value | No Q waves n = 942 | Q waves n = 733 | p value | No Q waves n = 765 | Q waves n = 849 | p value | |
| Age, yr | 57 (51, 66) | 59 (52, 68) | < 0.001 | 56 (50, 64) | 58 (52, 66) | 0.03 | 57 (51, 65) | 59 (53, 68) | 0.001 | 59 (52, 68) | 60 (52, 69) | 0.09 |
| Female, % | 25.7 | 20.8 | < 0.001 | 19.7 | 17.6 | 0.4 | 25.5 | 19.9 | 0.007 | 30.9 | 23.1 | < 0.001 |
| Diabetes mellitus, % | 17.2 | 18.3 | 0.3 | 16.6 | 13.8 | 0.2 | 14.9 | 19.4 | 0.01 | 20.4 | 19.6 | 0.7 |
| Hypertension, % | 55.9 | 56.7 | 0.6 | 48.7 | 52.3 | 0.2 | 55.6 | 57.3 | 0.49 | 62.4 | 58.4 | 0.1 |
| Heart rate, beats per min | 74 (65, 84) | 78 (68, 90) | < 0.001 | 74 (65, 84) | 77 (66, 88) | 0.002 | 74 (65, 83) | 79 (70, 90) | < 0.001 | 75 (65, 84) | 78 (68, 90) | < 0.001 |
| Systolic blood pressure, mm Hg | 130 (120, 150) | 133 (120, 150) | 0.7 | 130 (120, 147) | 135 (120, 150) | 0.1 | 135 (120, 150) | 135 (120, 150) | 0.8 | 132 (120, 150) | 130 (120, 150) | 0.6 |
| Killip class > 1, % | 5.0 | 8.3 | < 0.001 | 4.1 | 7.1 | 0.03 | 4.1 | 6.7 | 0.02 | 6.7 | 10.3 | 0.01 |
| Creatinine clearance, mL/min | 89.9 (73.1, 105.9) | 85.8 (68.2, 105) | 0.001 | 90.1 (74.5, 104.6) | 87.7 (68.2, 104.2) | 0.06 | 90.1 (74.2, 107) | 84.7 (68.3, 104.6) | 0.001 | 89.3 (70.2, 105.8) | 85.8 (68.2, 105.6) | 0.2 |
| Time from symptom onset to baseline ECG, hr | 2.3 (1.2, 4.2) | 3.0 (1.6, 6.0) | < 0.001 | 1.1 (0.7, 1.6) | 1.3 (0.8, 1.7) | < 0.001 | 2.5 (1.7, 3.3) | 2.8 (1.9, 3.6) | < 0.001 | 5.6 (3.1, 8.4) | 7 (4.5, 11.1) | < 0.001 |
| Time from symptom onset to PCI, hr | 4.3 (2.9, 7.3) | 5.3 (3.3, 9.5) | < 0.001 | 2.3 (1.9, 2.7) | 2.4 (2.0, 2.7) | 0.1 | 4.2 (3.5, 4.9) | 4.3 (3.6, 5.1) | 0.003 | 9.8 (7.4. 15.3) | 10.7 (7.8, 17.1) | 0.004 |
Note: ECG = electrocardiogram, PCI = percutaneous coronary intervention.
↵* Unless otherwise stated.