Characteristic | Patients, no. (%)* n = 30 |
---|---|
Sex | |
Male | 11 (37) |
Female | 19 (63) |
Age, y, mean (SD) | 51 (8) |
Education, y, mean (SD) | 15 (2) |
Beck depression inventory, score, mean (SD)† | 9 (5) |
Type of multiple sclerosis | |
Secondary progressive | 20 (67) |
Relapsing–remitting | 10 (33) |
Duration of multiple sclerosis, y, mean (SD) | 8.5 (7.4) |
Expanded disability status scale, score, mean (SD)‡ | 5.3 (1.5) |
Modified Ashworth scale, score, mean (SD)§ | |
Combined | 9.3 (2.3) |
Elbow | 2.5 (1.2) |
Hip | 3.3 (1.2) |
Knee | 3.6 (1.2) |
Requires mobility aids | |
Requires any aid | 20 (67) |
Requires a cane | 9 (30) |
Requires a walker | 5 (17) |
Requires a wheelchair | 6 (20) |
Undergoing disease-modifying therapy | |
Any disease-modifying therapy | 21 (70) |
Interferon β-1a | 9 (30) |
Interferon β-1b | 6 (20) |
Glatiramer | 6 (20) |
Antispasticity agents | |
Any antispasticity agent | 18 (60) |
Baclofen | 14 (47) |
Tizanidine | 4 (13) |
Previous exposure to cannabis | |
Any exposure | 24 (80) |
Exposure in previous year | 10 (33) |
>1 year since last use | 14 (47) |
Note: SD = standard deviation.
↵* Unless otherwise indicated.
↵† Scores range from 0 to 63, with higher scores suggesting a greater severity of depressive symptoms.
↵‡ Scores range from 0 to 10, with higher scores suggesting a greater degree of disability.
↵§ As determined during screening visit 1. Scores range from 0 to 24, with higher scores suggesting greater spasticity.