Myocardial infarction location, electrocardiography metrics and cardiac biomarkers for the study population, by time from the onset of symptoms to percutaneous coronary intervention and the presence of baseline Q waves
| Characteristic; median (25th, 75th percentile)* | All patients n = 4341 | Time from the onset of symptoms to PCI | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ≤ 3 h n = 1052 | > 3 to ≤ 6 h n = 1675 | > 6 h n = 1614 | ||||||||||
| No Q waves n = 2338 | Q waves n = 2003 | p value | No Q waves n = 631 | Q waves n = 421 | p value | No Q waves n = 942 | Q waves n = 733 | p value | No Q waves n = 765 | Q waves n = 849 | p value | |
| Inferior MI, % of patients | 61.1 | 34.4 | < 0.001 | 65.9 | 33.0 | < 0.001 | 63.4 | 34.9 | < 0.001 | 53.7 | 34.6 | < 0.001 |
| Baseline sum ST-segment elevation (∑ST-elevation), mm | 5 (2.5, 9) | 7.5 (4, 12.5) | < 0.001 | 6.5 (4, 11) | 9.5 (5.5, 16) | < 0.001 | 5.5 (3, 9.5) | 8.5 (5, 14) | < 0.001 | 3.5 (2, 6.5) | 5.5 (3, 10) | < 0.001 |
| Baseline sum ST-segment deviation (∑ST-deviation), mm | 9.5 (5.5, 15.5) | 11 (6.5, 17.5) | < 0.001 | 11.5 (7, 17.5) | 13.5 (8.5, 21) | < 0.001 | 10.5 (6.5, 17) | 13 (8, 20) | < 0.001 | 7 (4, 11.5) | 9 (5, 13.5) | < 0.001 |
| Sum ST-segment elevation resolution (∑ST-elevation) ≥ 50%, % | 79.0 | 66.5 | < 0.001 | 86.8 | 76.9 | < 0.001 | 82.4 | 72.5 | < 0.001 | 67.5 | 56.3 | < 0.001 |
| Sum ST-segment deviation resolution (∑ST-deviation) ≥ 50%, % | 78.7 | 67.1 | < 0.001 | 84.5 | 79.2 | 0.050 | 85.1 | 73.8 | < 0.001 | 65.3 | 55.4 | < 0.001 |
| Cardiac biomarkers | ||||||||||||
| Central troponin I ≥ 0.08 ng/mL at study entry, % | 84.5 | 91.8 | < 0.001 | 70.2 | 80.1 | 0.001 | 86.1 | 93.6 | < 0.001 | 94.4 | 96.0 | < 0.05 |
| Peak local creatine kinase-MB, ratio of the ULN | n = 1568 5.1 (1.8, 12.7) | n = 1379 7.6 (2.6, 19.3) | < 0.001 | n = 421 4.4 (1.6, 12.1) | n = 270 9.2 (2.6, 21.3) | < 0.001 | n = 659 6 (2.1, 13.8) | n = 520 8.2 (2.7, 20.7) | < 0.001 | n = 488 3.9 (1.7, 10.2) | n = 589 6.7 (2.5, 16.7) | < 0.001 |
| Peak local troponin I, ratio of the ULN | n = 1280 49.7 (5.3, 199.9) | n = 1024 100 (15.7, 374.5) | < 0.001 | n = 375 56.3 (4.1, 228) | n = 242 96.9 (12.2, 320.0) | 0.008 | n = 492 57 (4.9, 215.1) | n = 369 103.4 (12.1, 434.8) | < 0.001 | n = 413 42.4 (8, 166.7) | n = 413 97.4 (28.8, 362.7) | < 0.001 |
| Peak local troponin T, ratio of the ULN | n = 740 19.0 (2.9, 67.8) | n = 620 37.9 (8.7, 115.1) | < 0.001 | n = 187 22.3 (4.4, 82.7) | n = 129 39 (7.8, 116.5) | 0.068 | n = 309 20 (2.7, 66.7) | n = 222 41.7 (9, 103.5) | < 0.001 | n = 244 12.8 (2.5, 60.5) | n = 269 31.7 (8.6, 116) | < 0.001 |
Note: MI = myocardial infarction, PCI = percutaneous coronary intervention, ULN = upper limit of normal.
↵* Sum ST-deviation is the elevation plus depression.