Characteristic | Univariable RR (95% CI) | Multivariable RR (95% CI) |
---|---|---|
Age at diagnosis, yr | 1.15 (1.05–1.25) | 1.09 (1.01–1.18) |
Rurality and neighbourhood income | ||
Rural v. urban and income quintile 5 | 1.02 (0.38–2.74) | 0.85 (0.32–2.25) |
Urban and income quintile 1 v. urban and income quintile 5 | 1.2 (0.51–2.81) | 1.09 (0.54–2.23) |
Urban and income quintile 2 v. urban and income quintile 5 | 1.01 (0.36–2.87) | 0.95 (0.45–2.03) |
Urban and income quintile 3 v. urban and income quintile 5 | 0.46 (0.14–1.54) | 0.51 (0.23–1.13) |
Urban and income quintile 4 v. urban and income quintile 5 | 0.65 (0.26–1.61) | 0.59 (0.31–1.12) |
Period of diagnosis | ||
1997–2007 v. 1986–1996 | 0.71 (0.33–1.52) | 0.44 (0.23–0.85) |
2008–2014 v. 1986–1996 | 0.14 (0.02–0.84) | 0.09 (0.02–0.39) |
Anthracycline dose | ||
< 250 mg/m2 v. none | 3.36 (0.96–11.73) | 2.43 (0.72–8.17) |
≥ 250 mg/m2 v. none | 2.8 (0.74–10.63) | 2.15 (0.63–7.31) |
Transplant | ||
Allogenic v. none | 0.08 (0.01–0.6) | 0.14 (0.02–1.18) |
Autologous v. none | 0.3 (0.08–1.15) | 0.13 (0.04–0.41) |
Radiation | ||
No radiation to any body region v. breast and abdomen or pelvis | No patients in this category | – |
Abdomen or pelvis only vs breast and abdomen or pelvis | No patients in this category | – |
Breast only v. breast and abdomen or pelvis | 0.65 (0.31–1.38) | – |
ADG, categorical | ||
High v. none | 5.14 (1.5–17.67) | 3.21 (1.25–8.25) |
Intermediate v. none | 5.91 (2.21–15.79) | 3.82 (1.9–7.7) |
Low v. none | 4.52 (1.82–11.25) | 2.63 (1.32–5.21) |
PCP visits in the past yr | ||
1–3 PCP visits v. no PCP visits | 1.35 (0.9–2.04) | 1.15 (0.75–1.74) |
≥ 4 PCP visits v. no PCP visits | 1.11 (0.63–1.96) | 0.95 (0.55–1.65) |
LTFU clinic visit in the past yr | ||
Yes v. no | 1.56 (0.66–3.68) | 1.59 (0.88–2.89) |
Note: ADG = Aggregated Diagnosis Groups, CI = confidence interval, LTFU = long-term follow-up, PCP = primary care physician, RR = rate ratio.
↵* Age, rurality, period of diagnosis, anthracycline dose, transplant, ADG, PCP visits in the past year, LTFU clinic visit.