Laboratory investigations of a 22-year-old man with severe aortoiliac occlusive disease
| Test | Result (reference range) |
|---|---|
| Hematology and coagulation | |
| Hemoglobin, g/L | 137 (137–180) |
| Leukocyte count, × 109/L | 7.1 (4.0–11.0) |
| Platelet count, × 109/L | 394 (150–400) |
| Prothrombin time and international normalized ratio | 1.3 |
| Partial thromboplastin time, s | 61.4 (28.0–38.0) |
| Direct antiglobulin test | Positive, IgG and complement components detected |
| Haptoglobin, g/L | 1.01 (0.30–2.00) |
| Reticulocyte count, × 109/L | 58.5 (20–100) |
| Biochemistry | |
| Creatinine, μmol/L | 62 (50–120) |
| Urinalysis | Bland |
| Urine protein:creatinine, g/mmol | 0.005 (≤ 0.013) |
| C-reactive protein, mg/L | 8.4 (< 5) |
| Alanine aminotransferase, U/L | 23 (< 6) |
| Albumin, g/L | 34 (33–48) |
| Total bilirubin, μmol/L | 9 (< 21) |
| Lactate dehydrogenase, U/L | 195 (135–225) |
| Low-density lipoprotein, mmol/L | 2.71 (0.00–3.40) |
| Serology and immunology | |
| Antinuclear antibody | ≥ 1:640 speckled (≤ 1:80) |
| Extractable nuclear antigen panel | |
| Antichromatin, AI | 3.5 (≤ 0.9) |
| Anti-Smith, AI | 4.2 (≤ 0.9) |
| Anti-U1 small nuclear ribonucleoprotein A, AI | 1.8 (≤ 0.9) |
| Anti-double-stranded DNA, kIU/L | 944 (0–9) |
| C3, g/L | 0.91 (0.60–1.60) |
| C4, g/L | 0.05 (0.10–0.40) |
| Lupus anticoagulant | Present |
| Anticardiolipin IgG, GPU | High positive, > 160.0 (0.0–19.9) |
| Anti-β2 glycoprotein-1 IgG, GPU | High positive, > 160.0 (0.0–19.9) |
Note: AI = antibody index, GPU = immunoglobulin G phospholipid units, Ig = immunoglobulin.