RT Journal Article SR Electronic T1 Nonalcoholic fatty liver disease JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 899 OP 905 DO 10.1503/cmaj.045232 VO 172 IS 7 A1 Leon A. Adams A1 Paul Angulo A1 Keith D. Lindor YR 2005 UL http://www.cmaj.ca/content/172/7/899.abstract AB NONALCOHOLIC FATTY LIVER DISEASE is emerging as the most common chronic liver condition in the Western world. It is associated with insulin resistance and frequently occurs with features of the metabolic syndrome. Disease presentation ranges from asymptomatic elevated liver enzyme levels to cirrhosis with complications of liver failure and hepatocellular carcinoma. Current treatment recommendations are limited to weight loss and exercise, although several promising medications are on the horizon. In this article we discuss the etiology, pathogenesis and diagnosis of nonalcoholic fatty liver disease as well as approaches to its management.