RT Journal Article
SR Electronic
T1 Job insecurity and risk of diabetes: a meta-analysis of individual participant data
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP E447
OP E455
DO 10.1503/cmaj.150942
VO 188
IS 17-18
A1 Jane E. Ferrie
A1 Marianna Virtanen
A1 Markus Jokela
A1 Ida E.H. Madsen
A1 Katriina Heikkilä
A1 Lars Alfredsson
A1 G. David Batty
A1 Jakob B. Bjorner
A1 Marianne Borritz
A1 Hermann Burr
A1 Nico Dragano
A1 Marko Elovainio
A1 Eleonor I. Fransson
A1 Anders Knutsson
A1 Markku Koskenvuo
A1 Aki Koskinen
A1 Anne Kouvonen
A1 Meena Kumari
A1 Martin L. Nielsen
A1 Maria Nordin
A1 Tuula Oksanen
A1 Krista Pahkin
A1 Jan H. Pejtersen
A1 Jaana Pentti
A1 Paula Salo
A1 Martin J. Shipley
A1 Sakari B. Suominen
A1 Adam Tabák
A1 Töres Theorell
A1 Ari Väänänen
A1 Jussi Vahtera
A1 Peter J.M. Westerholm
A1 Hugo Westerlund
A1 Reiner Rugulies
A1 Solja T. Nyberg
A1 Mika Kivimäki
A1 ,
YR 2016
UL http://www.cmaj.ca/content/188/17-18/E447.abstract
AB Background: Job insecurity has been associated with certain health outcomes. We examined the role of job insecurity as a risk factor for incident diabetes.Methods: We used individual participant data from 8 cohort studies identified in 2 open-access data archives and 11 cohort studies participating in the Individual-Participant-Data Meta-analysis in Working Populations Consortium. We calculated study-specific estimates of the association between job insecurity reported at baseline and incident diabetes over the follow-up period. We pooled the estimates in a meta-analysis to produce a summary risk estimate.Results: The 19 studies involved 140 825 participants from Australia, Europe and the United States, with a mean follow-up of 9.4 years and 3954 incident cases of diabetes. In the preliminary analysis adjusted for age and sex, high job insecurity was associated with an increased risk of incident diabetes compared with low job insecurity (adjusted odds ratio [OR] 1.19, 95% confidence interval [CI] 1.09–1.30). In the multivariable-adjusted analysis restricted to 15 studies with baseline data for all covariates (age, sex, socioeconomic status, obesity, physical activity, alcohol and smoking), the association was slightly attenuated (adjusted OR 1.12, 95% CI 1.01–1.24). Heterogeneity between the studies was low to moderate (age- and sex-adjusted model: I2 = 24%, p = 0.2; multivariable-adjusted model: I2 = 27%, p = 0.2). In the multivariable-adjusted analysis restricted to high-quality studies, in which the diabetes diagnosis was ascertained from electronic medical records or clinical examination, the association was similar to that in the main analysis (adjusted OR 1.19, 95% CI 1.04–1.35).Interpretation: Our findings suggest that self-reported job insecurity is associated with a modest increased risk of incident diabetes. Health care personnel should be aware of this association among workers reporting job insecurity.