RT Journal Article SR Electronic T1 Drug-resistant tuberculosis JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 425 OP 428 VO 163 IS 4 A1 Richard Long YR 2000 UL http://www.cmaj.ca/content/163/4/425.abstract AB GLOBALLY THE PROPORTION OF TUBERCULOSIS CASES caused by drug-resistant strains is increasing. Interruptions in the drug supply, improper drug prescription and nonadherence to treatment protocols promote drug resistance through mechanisms that are now well understood. The treatment of tuberculosis must take into account the possibility of drug resistance and include at least 2 drugs, preferably 3, to which the isolate is proven or anticipated to be susceptible.