RT Journal Article SR Electronic T1 CATCH: a clinical decision rule for the use of computed tomography in children with minor head injury JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 341 OP 348 DO 10.1503/cmaj.091421 VO 182 IS 4 A1 Martin H. Osmond A1 Terry P. Klassen A1 George A. Wells A1 Rhonda Correll A1 Anna Jarvis A1 Gary Joubert A1 Benoit Bailey A1 Laurel Chauvin-Kimoff A1 Martin Pusic A1 Don McConnell A1 Cheri Nijssen-Jordan A1 Norm Silver A1 Brett Taylor A1 Ian G. Stiell A1 for the Pediatric Emergency Research Canada (PERC) Head Injury Study Group YR 2010 UL http://www.cmaj.ca/content/182/4/341.abstract AB Background: There is controversy about which children with minor head injury need to undergo computed tomography (CT). We aimed to develop a highly sensitive clinical decision rule for the use of CT in children with minor head injury. Methods: For this multicentre cohort study, we enrolled consecutive children with blunt head trauma presenting with a score of 13–15 on the Glasgow Coma Scale and loss of consciousness, amnesia, disorientation, persistent vomiting or irritability. For each child, staff in the emergency department completed a standardized assessment form before any CT. The main outcomes were need for neurologic intervention and presence of brain injury as determined by CT. We developed a decision rule by using recursive partitioning to combine variables that were both reliable and strongly associated with the outcome measures and thus to find the best combinations of predictor variables that were highly sensitive for detecting the outcome measures with maximal specificity. Results: Among the 3866 patients enrolled (mean age 9.2 years), 95 (2.5%) had a score of 13 on the Glasgow Coma Scale, 282 (7.3%) had a score of 14, and 3489 (90.2%) had a score of 15. CT revealed that 159 (4.1%) had a brain injury, and 24 (0.6%) underwent neurologic intervention. We derived a decision rule for CT of the head consisting of four high-risk factors (failure to reach score of 15 on the Glasgow coma scale within two hours, suspicion of open skull fracture, worsening headache and irritability) and three additional medium-risk factors (large, boggy hematoma of the scalp; signs of basal skull fracture; dangerous mechanism of injury). The high-risk factors were 100.0% sensitive (95% CI 86.2%–100.0%) for predicting the need for neurologic intervention and would require that 30.2% of patients undergo CT. The medium-risk factors resulted in 98.1% sensitivity (95% CI 94.6%–99.4%) for the prediction of brain injury by CT and would require that 52.0% of patients undergo CT. Interpretation: The decision rule developed in this study identifies children at two levels of risk. Once the decision rule has been prospectively validated, it has the potential to standardize and improve the use of CT for children with minor head injury.