RT Journal Article SR Electronic T1 Diagnosis and management of depression in primary care: a clinical update and review JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 1253 OP 1260 VO 167 IS 11 A1 Ronald A. Remick YR 2002 UL http://www.cmaj.ca/content/167/11/1253.abstract AB THERE HAS BEEN SIGNIFICANT PROGRESS in the area of mood disorders over the last 2 decades, encompassing advances in our knowledge of epidemiology, diagnosis, pathogenesis and treatment. This article presents a clinically oriented update and review on the diagnosis and management of major depressive disorder.