PT - JOURNAL ARTICLE AU - Narine, Lutchmie AU - Senathirajah, Mahil AU - Smith, Tina TI - Evaluating reference-based pricing DP - 1999 Aug 10 TA - Canadian Medical Association Journal PG - 286--288 VI - 161 IP - 3 4099 - http://www.cmaj.ca/content/161/3/286.short 4100 - http://www.cmaj.ca/content/161/3/286.full SO - CMAJ1999 Aug 10; 161 AB - Reference-based pricing is a controversial policy mechanism used to control pharmaceutical expenditures. After its implementation in some European countries, the British Columbia government introduced a version of reference-based pricing in October 1995. The authors reviewed previous studies of reference-based pricing in other countries and conducted a preliminary assessment of the impacts of the BC system by analysing secondary utilization and cost data. After the introduction of reference-based pricing in other jurisdictions within the Organisation for Economic Cooperation and Development, there was a temporary reduction in the rate of growth of total pharmaceutical expenditures, followed by a return to previous growth trends in subsequent years. Similarly, initial data from BC showed dramatic declines in annual expenditures for drugs within referenced categories (from $42.0 million the year before reference-based pricing was introduced to $23.7 million the year after). Although early evidence suggests that reference-based pricing in BC is indeed reducing drug expenditures, much more research is needed to make a final determination of its success. A more comprehensive and longitudinal evaluation of reference-based pricing is needed and should take into account a wide range of non-cost impacts, the most important of which are the effects on health outcomes.