PT  - JOURNAL ARTICLE
AU  - Chan-Yeung, M.
AU  - Grzybowski, S.
TI  - Occupational asthma
DP  - 1976 Mar 06
TA  - Canadian Medical Association Journal
PG  - 433--436
VI  - 114
IP  - 5
4099  - http://www.cmaj.ca/content/114/5/433.short
4100  - http://www.cmaj.ca/content/114/5/433.full
SO  - CMAJ1976 Mar 06; 114
AB  - Occupational asthma is probably much more common than is generally realized. Though many causes have been described, undoubtedly many more are yet to be recognized. One of the diagnostic difficulties lies in the fact that in most forms of this disease a late asthmatic reaction occurs in the evening rather than at work. The pathogenetic mechanisms differ in various forms of occupational asthma. In some, an immunologic mechanism is likely; in others, a "pharmacologic" action of the offending agent is implicated. Asthma due to inhalation of dusts of western red cedar, isocyanates, detergent enzymes and textiles is considered in detail. Periodic examination of workers at risk is of value for early diagnosis and prevention of irrversible airway obstruction.