RT Journal Article
SR Electronic
T1 The Brompton mixture: effects on pain in cancer patients
JF Canadian Medical Association Journal
JO CMAJ
FD Canadian Medical Association
SP 125
OP 129
VO 115
IS 2
A1 R. Melzack
A1 J. G. Ofiesh
A1 B. M. Mount
YR 1976
UL http://www.cmaj.ca/content/115/2/125.abstract
AB Terminally ill cancer patients were given the Brompton mixture and a phenothiazine in an attempt to control their pain. The mixture was administered to patients in three hospital environments: a palliative care unit (PCU), general wards and private rooms. Pain was measured in 92 patients with the McGill-Melzack Pain Questionnaire. The Brompton mixture controlled pain in 90% of patients in the PCU and in 75% to 80% of patients in the wards or private rooms. The differences in pain scores between the PCU patients and the other groups were significant. The mixture produced substantial decreases in the three major dimensions of pain: sensory, affective and evaluative. Comparison of these results with data obtained in an outpatient pain clinic showed that the Brompton mixture was strikingly more effective than the traditional methods of managing cancer pain.