PT  - JOURNAL ARTICLE
AU  - R. K. Laha
AU  - F. W. Saunders
AU  - W. S. Huestis
TI  - Herpes simplex encephalitis: treatment with surgical decompression and cytosine arabinoside
DP  - 1976 Aug 07
TA  - Canadian Medical Association Journal
PG  - 236--237
VI  - 115
IP  - 3
4099  - http://www.cmaj.ca/content/115/3/236.short
4100  - http://www.cmaj.ca/content/115/3/236.full
SO  - CMAJ1976 Aug 07; 115
AB  - Herpes simplex encephalitis in a 21-year-old man presented as a flu-like illness, followed by inappropriate behaviour, drowsiness and focal neurologic signs. Investigations indicated a lesion in the right temporal lobe. The diagnosis was confirmed by isolation of the virus from a cerebral biopsy. Pronounced clinical improvement was noted when cytosine arabinoside therapy was started in the postoperative period. This report supports the observation by some authors that cytosine arabinoside may be of value in the treatment of herpes simplex encephalitis.