PT  - JOURNAL ARTICLE
AU  - M. Mihic
AU  - L. S. Mautner
AU  - J. Z. Feness
AU  - K. Grant
TI  - Effect of trimethoprim-sulfamethoxazole on blood insulin and glucose concentrations of diabetics
DP  - 1975 Jun 14
TA  - Canadian Medical Association Journal
PG  - 80--82
VI  - 112
IP  - 13
4099  - http://www.cmaj.ca/content/112/13/80.short
4100  - http://www.cmaj.ca/content/112/13/80.full
SO  - CMAJ1975 Jun 14; 112
AB  - Trimethoprim-sulfamethoxazole (TMP-SMX) caused no significant changes in the blood glucose or insulin concentrations of diabetic subjects treated by dietary measures alone or by insulin and diet. In only one of eight subjects receiving oral hypoglycemic agents for the control of diabetes did a significant immediate increase in immunoreactive insulin follow administration of TMP-SMX. In the same patient hypoglycemic symptoms were present after the agent had been taken for 14 days.