TY - JOUR T1 - Comparison of penicillin and trimethoprim-sulfamethoxazole in the treatment of ear, nose and throat infections JF - Canadian Medical Association Journal JO - CMAJ SP - 83 LP - 86 VL - 112 IS - 13 AU - C. A. Quick Y1 - 1975/06/14 UR - http://www.cmaj.ca/content/112/13/83.abstract N2 - A double-blind trial of penicillin and the combination trimethoprim-sulfamethoxazole was undertaken in adult patients with active infection of the ears, nose or throat. The results indicated that the drug trimethoprim-sulfamethoxazole was as effective as penicillin in achieving clinical improvement and showed a broader spectrum than penicillin the the elimination of pathogenic organisms. The difficulties in obtaining positive cultures that were reflective of the clinical condition are described. ER -