RT Journal Article SR Electronic T1 Treatment of nephrotic edema with bumetanide JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 1111 OP 1112 VO 125 IS 10 A1 G. Lemieux A1 M. Beauchemin A1 A. Gougoux A1 P. Vinay YR 1981 UL http://www.cmaj.ca/content/125/10/1111.abstract AB In a crossover study bumetanide, 2 to 6 mg/d, was compared with furosemide, 40 to 160 mg/d, in the treatment of 10 patients with the nephrotic syndrome and massive edema. The two drugs, which both act on the loop of Henle, were found to be equally effective. Patients with renal insufficiency responded poorly to both drugs.