RT Journal Article SR Electronic T1 Drug resistance in malaria: three cases and a review JF Canadian Medical Association Journal JO CMAJ FD Canadian Medical Association SP 454 OP 457 VO 129 IS 5 A1 J. L. Isaac-Renton A1 A. L. Koon A1 R. M. Chan A1 A. W. Chow A1 S. L. Sacks YR 1983 UL http://www.cmaj.ca/content/129/5/454.abstract AB Drug resistance has been well documented in two species of malarial parasites. Of greatest concern are the rapid developments in the resistance of Plasmodium falciparum to commonly used therapeutic and chemoprophylactic agents. This species, which is capable of producing life-threatening disease, has shown various levels of resistance in different parts of the world. Also, some strains of the most common species causing relapsing disease, P. vivax, exhibit resistance to primaquine. Three cases of malaria that demonstrate various types of drug resistance are presented in this paper.