PT  - JOURNAL ARTICLE
AU  - J. L. Isaac-Renton
AU  - A. L. Koon
AU  - R. M. Chan
AU  - A. W. Chow
AU  - S. L. Sacks
TI  - Drug resistance in malaria: three cases and a review
DP  - 1983 Sep 01
TA  - Canadian Medical Association Journal
PG  - 454--457
VI  - 129
IP  - 5
4099  - http://www.cmaj.ca/content/129/5/454.short
4100  - http://www.cmaj.ca/content/129/5/454.full
SO  - CMAJ1983 Sep 01; 129
AB  - Drug resistance has been well documented in two species of malarial parasites. Of greatest concern are the rapid developments in the resistance of Plasmodium falciparum to commonly used therapeutic and chemoprophylactic agents. This species, which is capable of producing life-threatening disease, has shown various levels of resistance in different parts of the world. Also, some strains of the most common species causing relapsing disease, P. vivax, exhibit resistance to primaquine. Three cases of malaria that demonstrate various types of drug resistance are presented in this paper.