PT - JOURNAL ARTICLE AU - J. H. Cummings AU - A. M. Stephen TI - The role of dietary fibre in the human colon DP - 1980 Dec 06 TA - Canadian Medical Association Journal PG - 1109--1114 VI - 123 IP - 11 4099 - http://www.cmaj.ca/content/123/11/1109.short 4100 - http://www.cmaj.ca/content/123/11/1109.full SO - CMAJ1980 Dec 06; 123 AB - Several effects of dietary fibre on colonic function have been documented by experiment or deduced from epidemiologic observation. The magnitude of these changes depends on the source and the physical and chemical composition of the fibre used, and on the individual response of the subjects. Three theories of the mode of action of fibre are discussed; they relate to the water-holding capacity of fibre, the production of short-chain fatty acids from fibre in the colon and the alteration by fibre of the colonic microflora.