PT  - JOURNAL ARTICLE
AU  - W. D. Parsons
AU  - J. G. Pelletier
TI  - Delayed elimination of caffeine by women in the last 2 weeks of pregnancy
DP  - 1982 Sep 01
TA  - Canadian Medical Association Journal
PG  - 377--380
VI  - 127
IP  - 5
4099  - http://www.cmaj.ca/content/127/5/377.short
4100  - http://www.cmaj.ca/content/127/5/377.full
SO  - CMAJ1982 Sep 01; 127
AB  - Caffeine elimination was studied in 15 women at 38 to 40 weeks' gestation. The mean hourly caffeine clearance, 37 ml/kg, determined from assays of saliva, was only 39% of the value previously reported for nonpregnant adults (94 ml/kg). Reassessment in four of the women 2 to 12 weeks post partum showed that in each woman the caffeine clearance had increased more than threefold and that the mean caffeine concentration in the saliva after no intake of caffeine for 24 hours was now much lower (0.07 v. 0.84 microgram/ml).